DNA and ATP binding activities of the baculovirus DNA helicase P143.

نویسندگان

  • V V McDougal
  • L A Guarino
چکیده

P143 is a DNA helicase that tightly binds both double-stranded and single-stranded DNA. DNA-protein complexes rapidly dissociated in the presence of ATP and Mg(2+). This finding suggests that ATP hydrolysis causes a conformational change in P143 which decreases affinity for DNA. This supports the model of an inchworm mechanism of DNA unwinding.

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عنوان ژورنال:
  • Journal of virology

دوره 75 15  شماره 

صفحات  -

تاریخ انتشار 2001